产品货号：
Z31398
中文名称：
CYP7A1抗体
英文名称：
Anti-CYP7A1 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CYP7A1 Antibody |
| 指标别名 | cytochrome P450 family 7 subfamily A member 1;CP7A;CYP7;CYPVII;CYP7A1 |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | CYP7A1 |
| 抗体来源 | Mouse |
| 免疫原 | Purified recombinant human CYP7A1 (C-terminal) protein fragments expressed in E.coli. |
| 计算分子量 | 58KD |
| 成分 | Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH7.4,150mM NaCl) with 0.2% sodium azide,50% glycerol. |
| 纯化方式 | Affinity purification |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | CYP7A1(Cytochrome P450 Subfamily VIIA Polypeptide 1),also called CYP7 or CHOLESTEROL 7-ALPHA-HYDROXYLASE,is an enzyme that in humans is encoded by the CYP7A1 gene.Using both mouse-human somatic cell hybrids and in situ chromosomal hybridization,Cohen et al.(1992) mapped the CYP7 gene to 8q11-q12.By transfection of reporter constructs,mutation analysis,and DNase footprinting,Molowa et al.(1992) identified areas of the CYP7A1 promoter region that showed hepatocyte-specific activation.They found HNF3 to be an activator of CYP7A1 activity.Agellon et al.(2002) found that wildtype mice and mice transgenic for human CYP7A1 respond differently to cholesterol feeding.Cholesterol feeding stimulated Cyp7a1 mRNA abundance and enzymatic activity in wildtype mice,but repressed human CYP7A1 mRNA and activity in transgenic mice. |
| Uniprot ID | P22680 |
| 基因名全称 | Cholesterol 7-alpha-monooxygenase |
| 蛋白名全称 | Cholesterol 7-alpha-monooxygenase |
| 推荐稀释比 | WB 1:1000～1:2000 |
相关搜索：CYP7A1抗体，CYP7A1单抗，Anti-CYP7A1 Antibody